SARANGE Syrup


Each Syrup Contains:
Ferric Ammonium Citrate
Folic Acid
Cyanocobalamin
Sorbitol Flavoured Syrupy Base q.s.

200 ml Rs 70

SARANGE


This composition contains vitamins and minerals which are involve in improving the haematological factors and in the synthesis of Deoxyribonucleic acid and protects against the neural tube defects in the foetus of pregnant women and child bearing women.

Ferric Ammonium Citrate- This salt of iron and citric acid is insoluble in water. It is used in the treatment of anemia and it deals with the complications of pregnancy or hematologic problems.

Folic acid belongs to the vitamin b family and is essential for maintaining the new cells or involves in the synthesis of dNA and rNA, also it prevents the changes in the deoxyribonucleic acid which may is the cause of many forms of cancer.

Cyanocobalamin is vitamin B12 and is also involves in the DNA synthesis and energy production. It is treats the deficiency of vitamin B12. It acts as cofactor for the hormones, proteins and lipid. It is also involved in the synthesis of methionine from homocysteine.

Sorbitol is basically existing in the alcoholic form but also have the sweetness of sucrose and it is also obtained synthetically from glucose. It is indicated as laxative and diuretic. It maintains the accumulation of fluid in the colon and softens the stool or facilitates its excretion. It helps to remove debris from the infected area and thus is used in the surgical procedures.

  • Anemia
  • In iron deficiency anemia
  • Vitamin B12 deficiency
  • Megaloblastic anemia

Mechanism of action-

Salbutamol acts on the beta-2 adrenergic receptors and activates the cyclic AMP which further causes the release of protein kinase A which relaxes the smooth muscles.
Bromhexine disrupts the structure of mucopolysaccride in the sputum and reduces viscosity of the mucus.
Choline Theophyllinate relaxes the muscles and opens the airways in the lungs.

Pharmacokinetics-

Salbutamol-
It is absorbed orally
It shows less protein binding
It is converted to 4-O-sulphate in the liver
It is excreted via feces

Bromhexine-
It is absorbed orally
It is highly bound to plasma proteins
It undergoes first pass metabolism in liver
  • Nausea
  • Vomiting
  • Sweat
  • Headache
  • Bloating
  • Diarrhoea
  • Palpitations
  • Contraindicated in overactive thyroid gland
  • Contraindicated in diabetes